About 2 results found for searched term "GSK778" (0.23 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7551 | Solcitinib | JAK |
| GSK-2586184; GLPG-0778 | ||
| Solcitinib is an oral, competitive, potent, and selective JAK1 inhibitor with an IC50 value of 9.8 nM, which is 11,55, and 23 times more selective than JAK2, JAK3, and TYK2. Solcitinib can be used in studies of psoriasis. | ||
| M10828 | GSK778 | Epigenetic Reader Domain |
| iBET-BD1 | ||
| GSK778 (iBET-BD1) is a potent and selective inhibitor of the BD1 bromine domain of the BET protein,IC50 The values are 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1). GSK778 phenotyping the role of pan-BET inhibitors in cancer models. | ||
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